You can go big or you can go "O!" And Oprah Winfrey is going out in A-list style. The daytime TV doyenne is wrapping up her namesake talk show, 'The Oprah Winfrey Show,' after 25 wild, wonderful years!

Oprah taped two of her final three episodes on Tuesday night. The festivities were filmed at the United Center in Chicago, with 20,000 rabid fans in attendance. There was no shortage of celeb friends, either, as Beyonce, Usher and Madonna, along with Josh Groban, Rascal Flatts, Jackie Evancho, Tom Cruise and Tom Hanks, showed up to help send 'The Oprah Winfrey Show' off into the sunset. The celeb-drenched special will air in two parts over May 23 and 24. The very last show will air on May 25.

Madonna threw major props at Winfrey, declaring, "It's no secret that millions of people are inspired by Oprah. I am one of them. She's a self-made woman who's been at the top of her game for over 25 years and she is still kicking ass. And she is still kicking ass!" Girl power!

R&B star Usher closed out the show, as rapper/actor Will Smith introduced him at the end of the four-hour spectacle. Usher sang a medley of 'O.M.G.' and 'Oh Happy Day' as confetti fell from the ceiling.

Oh Oprah! What will we do without you? What will daytime TV look like without 'The Oprah Winfrey Show' anchoring the afternoon lineup? Guess we'll have to mosey on over to the OWN, the network Oprah is spearheading with tons of original programming.

R.I.P. to 'The Oprah Winfrey Show.'

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